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1

10.1038/9367

Schramm, Vern L., Li, Caroline M., Tyler, Peter C., Furneaux, Richard H., Kicska, Gregory, Xu, Yiming, Grubmeyer, Charles, Girvin, Mark E.

Journal:

Natural Structural Biology

Year:

1999

Language:

english

File:

PDF, 1.04 MB

english, 1999

2

10.1038/9376

Schramm, Vern L., Almo, Steven C., Shi, Wuxian, Li, Caroline M., Tyler, Peter C., Furneaux, Richard H., Grubmeyer, Charles

Journal:

Natural Structural Biology

Year:

1999

Language:

english

File:

PDF, 1.18 MB

english, 1999

3

Kinetic Mechanism of Human Hypoxanthine−Guanine Phosphoribosyltransferase: Rapid Phosphoribosyl Transfer Chemistry†

Xu, Yiming, Eads, Janina, Sacchettini, James C., Grubmeyer, Charles

Journal:

Year:

1997

Language:

english

File:

PDF, 402 KB

english, 1997

4

A Transition-State Analogue Reduces Protein Dynamics in Hypoxanthine-Guanine Phosphoribosyltransferase†

Wang, Fang, Shi, Wuxian, Nieves, Edward, Angeletti, Ruth H., Schramm, Vern L., Grubmeyer, Charles

Journal:

Year:

2001

Language:

english

File:

PDF, 469 KB

english, 2001

5

Structure of Salmonella typhimurium OMP Synthase in a Complete Substrate Complex

Grubmeyer, Charles, Hansen, Michael Riis, Fedorov, Alexander A., Almo, Steven C.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.70 MB

english, 2012

6

Loop Residues and Catalysis in OMP Synthase

Wang, Gary P., Hansen, Michael Riis, Grubmeyer, Charles

Journal:

Year:

2012

Language:

english

File:

PDF, 628 KB

english, 2012

7

A new function for a common fold: the crystal structure of quinolinic acid phosphoribosyltransferase

Janina C Eads, Derya Ozturk, Tom B Wexler, Charles Grubmeyer, James C Sacchettini

Journal:

Year:

1997

Language:

english

File:

PDF, 433 KB

english, 1997

8

Crystal structure of quinolinic acid phosphoribosyltransferase from Mycobacterium tuberculosis: a potential TB drug target

Vivek Sharma, Charles Grubmeyer, James C Sacchettini

Journal:

Year:

1998

Language:

english

File:

PDF, 922 KB

english, 1998

9

Primary Structure and Crystallization of Orotate Phosphoribosyltransferase from Salmonella typhimurium

Giovanna Scapin, James C. Sacchettini, Andrea Dessen, Mohit Bhatia, Charles Grubmeyer

Journal:

Journal of Molecular Biology

Year:

1993

File:

PDF, 275 KB

1993

10

l-Histidinol dehydrogenase, a Zn2+-metalloenzyme

Charles Grubmeyer, Marios Skiadopoulos, Alan E. Senior

Journal:

Archives of Biochemistry and Biophysics

Year:

1989

Language:

english

File:

PDF, 645 KB

english, 1989

11

Probing the Nucleotide Binding Site of Creatine Kinase

ALEXANDER VINITSKY, CHARLES GRUBMEYER

Journal:

Annals of the New York Academy of Sciences

Year:

1984

Language:

english

File:

PDF, 114 KB

english, 1984

12

The crystal structure of human hypoxanthine-guanine phosphoribosyltransferase with bound GMP

Janina C. Eads, Giovanna Scapin, Yiming Xu, Charles Grubmeyer, James C. Sacchettini

Journal:

Year:

1994

Language:

english

File:

PDF, 4.23 MB

english, 1994

13

The 2.0 Å Structure of Malarial Purine Phosphoribosyltransferase in Complex with a Transition-State Analogue Inhibitor †,‡

Shi, Wuxian, Li, Caroline M., Tyler, Peter C., Furneaux, Richard H., Cahill, Sean M., Girvin, Mark E., Grubmeyer, Charles, Schramm, Vern L., Almo, Steven C.

Journal:

Year:

1999

Language:

english

File:

PDF, 247 KB

english, 1999

14

Catalytic site interactions in yeast OMP synthase

Hansen, Michael Riis, Barr, Eric W., Jensen, Kaj Frank, Willemoës, Martin, Grubmeyer, Charles, Winther, Jakob R.

Journal:

Archives of Biochemistry and Biophysics

Year:

2014

Language:

english

File:

PDF, 1.14 MB

english, 2014

15

Backbone 1H-13C-15N NMR Assignments and Ligand Binding Study of OMP Synthase from Saccharomyces Cerevisiae

Hansen, Michael R., Barr, Eric W., Harris, Richard, Frank Jensen, Kaj, Willemoës, Martin, Cheng, Hong, Girvin, Mark, Grubmeyer, Charles

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 84 KB

english, 2013

16

Conversion of a Cosubstrate to an Inhibitor: Phosphorylation Mutants of Nicotinic Acid Phosphoribosyltransferase †

Rajavel, Mathumathi, Lalo, Dominique, Gross, Jeffrey W., Grubmeyer, Charles

Journal:

Year:

1998

Language:

english

File:

PDF, 110 KB

english, 1998

17

Cysteine residue (cysteine-116) in the histidinol binding site of histidinol dehydrogenase

Grubmeyer, Charles Timmis, Gray, William R.

Journal:

Year:

1986

Language:

english

File:

PDF, 1.57 MB

english, 1986

18

Energy Coupling in Salmonella typhimurium Nicotinic Acid Phosphoribosyltransferase: Identification of His-219 as Site of Phosphorylation †

Gross, Jeffrey, Rajavel, Mathumathi, Segura, Edy, Grubmeyer, Charles

Journal:

Year:

1996

Language:

english

File:

PDF, 378 KB

english, 1996

19

Mutagenesis of Histidinol Dehydrogenase Reveals Roles for Conserved Histidine Residues †

Teng, Henry, Grubmeyer, Charles

Journal:

Year:

1999

Language:

english

File:

PDF, 79 KB

english, 1999

20

Interactions at the 2 and 5 Positions of 5-Phosphoribosyl Pyrophosphate Are Essential in Salmonella typhimurium Quinolinate Phosphoribosyltransferase

Bello, Zainab, Stitt, Barbara, Grubmeyer, Charles

Journal:

Year:

2010

Language:

english

File:

PDF, 2.62 MB

english, 2010

21

Pyrophosphate Activation in Hypoxanthine−Guanine Phosphoribosyltransferase with Transition State Analogue

Deng, Hua, Callender, Robert, Schramm, Vern L., Grubmeyer, Charles

Journal:

Year:

2010

Language:

english

File:

PDF, 1.41 MB

english, 2010

22

Kinetic Mechanism of Nicotinic Acid Phosphoribosyltransferase: Implications for Energy Coupling †

Gross, Jeffrey W., Rajavel, Mathumathi, Grubmeyer, Charles

Journal:

Year:

1998

Language:

english

File:

PDF, 259 KB

english, 1998

23

Roles for Cationic Residues at the Quinolinic Acid Binding Site of Quinolinate Phosphoribosyltransferase

Bello, Zainab, Grubmeyer, Charles

Journal:

Year:

2010

Language:

english

File:

PDF, 1.19 MB

english, 2010

24

Structure and Function of Salmonella typhimurium Orotate Phosphoribosyltransferase: Protein Complementation Reveals Shared Active Sites

Ozturk, Derya H., Dorfman, Ryan H., Scapin, Giovanna, Sacchettini, James C., Grubmeyer, Charles

Journal:

Year:

1995

Language:

english

File:

PDF, 1.62 MB

english, 1995

25

Kinetic mechanism of orotate phosphoribosyltransferase from Salmonella typhimurium

Bhatia, Mohit B., Vinitsky, Alexander, Grubmeyer, Charles

Journal:

Year:

1990

Language:

english

File:

PDF, 1.61 MB

english, 1990

26

Histidinol dehydrogenase: oxygen-18 isotope shift in carbon-13 NMR reveals the origin of histidine oxygens

Grubmeyer, Charles Timmis, Insinga, Salvatore

Journal:

Journal of the American Chemical Society

Year:

1990

Language:

english

File:

PDF, 395 KB

english, 1990

27

Kinetic mechanism of histidinol dehydrogenase: histidinol binding and exchange reactions

Grubmeyer, Charles Timmis, Chu, Kim Wai, Insinga, Salvatore

Journal:

Year:

1987

Language:

english

File:

PDF, 606 KB

english, 1987

28

Mechanism of Salmonella typhimurium Histidinol Dehydrogenase: Kinetic Isotope Effects and pH Profiles †

Grubmeyer, Charles, Teng, Henry

Journal:

Year:

1999

Language:

english

File:

PDF, 70 KB

english, 1999

29

Crystal Structure of Orotate Phosphoribosyltransferase

Scapin, Giovanna, Grubmeyer, Charles, Sacchettini, James C.

Journal:

Year:

1994

Language:

english

File:

PDF, 4.15 MB

english, 1994

30

Motional Dynamics of the Catalytic Loop in OMP Synthase †

Wang, Gary P., Cahill, Sean M., Liu, Xiaohong, Girvin, Mark E., Grubmeyer, Charles

Journal:

Year:

1999

Language:

english

File:

PDF, 130 KB

english, 1999

31

Locations and Functional Roles of Conserved Lysine Residues in Salmonella typhimurium Orotate Phosphoribosyltransferase

Ozturk, Derya H., Dorfman, Ryan H., Scapin, Giovanna, Sacchettini, James C., Grubmeyer, Charles

Journal:

Year:

1995

Language:

english

File:

PDF, 1.88 MB

english, 1995

32

Salmonella typhimurium histidinol dehydrogenase: complete reaction stereochemistry and active site mapping

Grubmeyer, Charles Timmis, Insinga, Salvatore, Bhatia, Mohit, Moazami, Nader

Journal:

Year:

1989

Language:

english

File:

PDF, 849 KB

english, 1989

33

Quinolinate Phosphoribosyltransferase: Kinetic Mechanism for a Type II PRTase †

Cao, Hong, Pietrak, Beth L., Grubmeyer, Charles

Journal:

Year:

2002

Language:

english

File:

PDF, 92 KB

english, 2002

34

Kinetic Mechanism of OMP Synthase: A Slow Physical Step Following Group Transfer Limits Catalytic Rate †

Wang, Gary P., Lundegaard, Claus, Jensen, Kaj Frank, Grubmeyer, Charles

Journal:

Year:

1999

Language:

english

File:

PDF, 97 KB

english, 1999

35

The Crystal Structure of the Orotate Phosphoribosyltransferase Complexed with Orotate and .alpha.-D-5-Phosphoribosyl-1-Pyrophosphate

Scapin, Giovanna, Ozturk, Derya H., Grubmeyer, Charles, Sacchettini, James C.

Journal:

Year:

1995

Language:

english

File:

PDF, 3.06 MB

english, 1995

36

Transition State Structure of Salmonella typhimurium Orotate Phosphoribosyltransferase †

Tao, Wen, Grubmeyer, Charles, Blanchard, John S.

Journal:

Year:

1996

Language:

english

File:

PDF, 293 KB

english, 1996

37

Catalysis in Human Hypoxanthine-Guanine Phosphoribosyltransferase: Asp 137 Acts as a General Acid/Base †

Xu, Yiming, Grubmeyer, Charles

Journal:

Year:

1998

Language:

english

File:

PDF, 241 KB

english, 1998

38

Crystal Structures of Giardia lamblia Guanine Phosphoribosyltransferase at 1.75 Å †,‡

Shi, Wuxian, Munagala, Narsimha R., Wang, Ching C., Li, Caroline M., Tyler, Peter C., Furneaux, Richard H., Grubmeyer, Charles, Schramm, Vern L., Almo, Steven C.

Journal:

Year:

2000

Language:

english

File:

PDF, 994 KB

english, 2000

39

Limited Proteolysis of Salmonella typhimurium Nicotinic Acid Phosphoribosyltransferase Reveals ATP-Linked Conformational Change †

Rajavel, Mathumathi, Gross, Jeffrey, Segura, Edy, Moore, William T., Grubmeyer, Charles

Journal:

Year:

1996

Language:

english

File:

PDF, 361 KB

english, 1996

40

Ionic States of Substrates and Transition State Analogues at the Catalytic Sites of N -Ribosyltransferases †

Sauve, Anthony A., Cahill, Sean M., Zech, Stephan G., Basso, Luiz A., Lewandowicz, Andrzej, Santos, Diogenes S., Grubmeyer, Charles, Evans, Gary B., Furneaux, Richard H., Tyler, Peter C., McDermott, A

Journal:

Year:

2003

Language:

english

File:

PDF, 309 KB

english, 2003

41

Partial characterization of a soluble ATPase from pea cotyledon mitochondria

Grubmeyer, Charles, Duncan, Ian, Spencer, Mary

Journal:

Canadian Journal of Biochemistry

Year:

1977

Language:

english

File:

PDF, 472 KB

english, 1977

42

Oxidative Phosphorylation in Pea Cotyledon Submitochondrial Particles

Charles Grubmeyer, Dara Melanson, Ian Duncan and Mary Spencer

Journal:

PLANT PHYSIOLOGY

Year:

1979

Language:

english

File:

PDF, 962 KB

english, 1979

43

Oligomycin-Sensitive ATPase of Submitochondrial Particles from Corn

Charles Grubmeyer and Mary Spencer

Journal:

PLANT PHYSIOLOGY

Year:

1978

Language:

english

File:

PDF, 383 KB

english, 1978

44

Phosphorylation site specificity of the CDC2-related kinase PITALRE

GARRIGA, Judit, SEGURA, Edy, MAYOL, Xavier, GRUBMEYER, Charles, GRAÑA, Xavier

Journal:

Biochemical Journal

Year:

1996

Language:

english

File:

PDF, 287 KB

english, 1996

45

ATPase Activity of Pea Cotyledon Submitochondrial Particles. Activation, Substrate Specificity, and Anion Effects

Charles Grubmeyer and Mary Spencer

Journal:

PLANT PHYSIOLOGY

Year:

1980

Language:

english

File:

PDF, 836 KB

english, 1980

46

[Methods in Enzymology] Enzyme kinetics and mechanism Part E: Energetics of Enzyme Catalysis Volume 308 || [2] Energy coupling through molecular discrimination: Nicotinate phosphoribosyltransferase

Grubmeyer, Charles Timmis

Year:

1999

Language:

english

File:

PDF, 1.14 MB

english, 1999